The most compelling argument against human challenge trials for a COVID-19 vaccine, though, is that it might not actually be any faster. In order to infect people with the virus, we have to have a tested viral dose — one that is strong enough to infect people, but not so strong it gives an infection worse than natural spread — which can take up to a year to develop, according to Weijer.
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Oxford coronavirus vaccine safe and promising, according to early human trial results published in the Lancet
A University of Oxford group and the British-Swedish pharmaceutical company AstraZeneca reported Monday that their coronavirus vaccine candidate, on which the U.S. and European governments have placed substantial bets, was shown in early-stage human trials to be safe and to stimulate a strong immune response.
Moderna and Pfizer Begin Late-Stage Coronavirus Vaccine Trials
The first large study of the safety and effectiveness of a coronavirus vaccine in the United States began on Monday morning, according to the National Institutes of Health and the biotech company Moderna, which collaborated to develop the vaccine.
Six COVID-19 vaccine candidates in phase-3 trials, 3 from China
The vaccines will be put into the general population for the first time in phase 3, after previous trials have focused on safety, immunogenicity and immune response in a small number of humans, said the WHO official. The phase-3 trial will test whether the vaccines can "protect large numbers of people over a prolonged period of time."
Moderna coronavirus vaccine shows promising results in early clinical trial
An experimental coronavirus vaccine developed by Moderna provoked an immune response without major side effects in an early-stage clinical trial, scientists reported Tuesday in the New England Journal of Medicine.The vaccine is the first developed by a U.S. company to publish clinical trial results.
Johnson & Johnson says coronavirus vaccine's human trials moved up to July
Johnson & Johnson has accelerated the start of human trials for a Covid-19 vaccine by two months, with trials set to start in July. If the vaccine works, Johnson & Johnson has pledged to distribute the vaccine at a non-profit rate
Why have 14,000 people volunteered to be infected with coronavirus?
Imagine being told to inhale a nasal spray full of coronavirus. More than 14,000 people in the U.S. and elsewhere are putting their names forward to do so. They are volunteering for what's called a "human challenge trial," an ethically controversial way to test vaccines that would deliberately infect people with a virus that has killed over 270,000 people worldwide and has no cure.
Oxford professor: Possible coronavirus vaccine could show efficacy by June
Sir John Bell, the Regius Professor of Medicine at Oxford University, said Sunday that researchers at the university working on a potential vaccine for the coronavirus would likely have an idea of its efficacy by June. Bell called the chances of success in developing a vaccine “pretty good,” adding “we are gradually reeling it in, bit by bit and as every day goes by, the likelihood of success goes up.”
Coronavirus: First patients injected in UK vaccine trial
Two volunteers were injected, the first of more than 800 people recruited for the study. Half will receive the Covid-19 vaccine, and half a control vaccine which protects against meningitis but not coronavirus. The design of the trial means volunteers will not know which vaccine they are getting, though doctors will.